[LIMITED] Tanned and tipsy cap

[LIMITED] Tanned and tipsy cap

Buy it here : Tanned and tipsy cap

Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark Tanned and tipsy cap brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin’s cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight or by artificial UV radiation, which can be delivered in frequencies of UVA, UVB, or a combination of both. The intensity is commonly measured by the UV Index.

Cross-sectional view showing skin tone becoming darker due to the production of more melanin to overcome DNA damage caused by UV radiation Tanned and tipsy cap
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn.

In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body’s reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure. The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB).

[LIMITED] Tanned and tipsy cap

 

 

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